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Search For New Therapeutic Agents Against Complicated Obesity

By Reprofiling Existing Drugs

 

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 Visit de website. In this site you will find links to the 7th Framework Programme (2007-2013) research projects on these topics.

 

Research Area: HEALTH-2007

ADAPT***
Adipokines as drug targets to combat adverse effects of excess adipose tissue
www.ADAPT-EU.net

BETACELLTHERAPY***
Beta cell therapy in Diabetes
http://www.betacelltherapy.org/

BETAIMAGE***
Use of innovative strategies for beta-cell imaging in diabetes mellitus

CEED3***
Collaborative European effort to develop diabetes diagnostics

CHEARTED
Gene-environment interactions in heart development

COPACETIC
COPD pathology: addressing critical gaps, early treatment and innovative concepts

DIABIMMUNE***
Pathogenesis of type 1 diabetes - testing the hygiene hypothesis
http://www.alphagalileo.org/ViewItem.aspx?ItemId=5945&CultureCode=en
http://www.diabimmune.org/

DIAMAP***
A Road Map for European Diabetes Research
www.DIAMAP.eu

DIAMARK***
Sensory and biomechanical markers in diabetic neuropathy of the gut. Basic investigations and new approaches for treatment

DIAPREPP***
DIAbetes type 1 PRediction, Early Pathogenesis and Prevention
http://www.diaprepp.eu

DMIOL***
Diabetes type 1 prediction, early pathogenesis and prevention


ENCITE
European Network for Cell Imaging and Tracking Expertise

EURADRENAL
Pathophysiology and natural course of autoimmune adrenal failure in Europe

GIPIO
Gastro-intestinal peptides in obesity

ICREL
Impact on clinical research of European legislation
http://www.efgcp.be/icrel

MEDCHAMPS***
Mediterranean studies of cardiovascular disease and hyperglycaemia: analytical modelling of population socio-economic transitions
http://research.ncl.ac.uk/medchamps/

MITIN***
Integration of the system models of insulin signalling and of mitochondrial function and its application in the study of complex diseases
http://www.mitin-fp7.eu/

PREPOBEDIA***
Novel Prep1-Dependent Transcriptional Networks in the Control of Insulin Sensitivity
http://www.prepobedia.org/

REPROBESITY
Search for new therapeutic agents against complicated obesity by reprofiling existing drugs
http://www.reprobesity.eu/

SYBILLA
Systems biology of T-cell activation in health and disease
http://www.sybilla-t-cell.de/

SYSKID
Systems biology towards novel chronic kidney disease diagnosis and treatment

TOBI
Targeting OBesity-driven Inflammation
http://www.tobi-project.eu/


Research Area: FP7-People Marie Curie Action

ACTIVEAGING
The effect of physical activity on muscle biology and health in statin-treated older individuals

ADIBET
The role of adipose tissue in obesity: beta cell crosstalk

ADPROGRES
Alzheimer disease progression: Molecular studies of Abeta amyloid peptides aggregation and trafficking in neuronal cells

BMP 8B THERMOGENESIS
Role of bone morphogenic protein 8b (BMP8b) in thermogenesis

CD49D IN DIABETES
Role of the alpha4 integrin (CD49d) in type-1 diabetes mellitus prevention and treatment

CX43-CRF
Implication of connexin 43 in chronic renal failure

CIRCADIAN REGULATION***
Circadian regulation in the control of insulin and glucagon release and its role in type 2 diabetes

DIABETIC EMBRYOPATHY***
Molecular Mechanisms in Diabetic Embryopathy

ENG-LEA***
Trends in hospital admissions for lower extremity amputations in people with and without diabetes in England, 1996-2005

FUNGENCEL
Functional genomics of fatty acid desaturases in caenorhabditis elegans

HASKODIABETES***
Adenosine receptors in diabetes

HEALTHY FOOD FOR LIFE
Supporting healthy lifestyles in the Mediterranean Area

HYPOTHALAMIC T3
The role of hypothalamic thyroid hormone in the neuroendocrine regulation of appetite, energy balance and glucose homeostasis

IMSCIV
Immunogenicity of mesenchymal stem cells in vivo

INSULIN SECRETION***
Regulation of glucose-stimulated secretory vesicle mobilisation in pancreatic beta-cells

IRGENOMICS***
Genetical genomics of type 2 diabetes and cardiovascular phenotypes in experimental systems

LIPOGEST
Mechanisms by which interfacial layers control lipolysis on digestion

METABOLICSYNDROME***
Role of the chylomicron and HDL pathways in the development of obesity and insulin resistance

MIELT1D***
MHC Class I expression level in type 1 diabetes

NAAN***
Natural antidiabetic & anti-hypertensive drugs

NRFDIABVASC***
Role of Nrf2 transcription factor in diabetic vasculopathy, oxidative stress and inflammation

OBESITY AND IMMUNITY
Prevention of obesity-related inflammation

OXFORDWINSTON***
The effects of lineage differentiation into pancreatic beta-cells on the immunogenicity of amniotic fluid stem cells

P16 AND METABOLISM***
The role of p16INK4a in the development of obesity and insulin resistance

PHD-OB-T2D***
Study the role of oxygen sensors Prolyl Hydroxylase Domain (PHD) protein in obesity and type 2 diabetes

PREVENTION T2D***
Life style and genetic factors in prevention of type 2 diabetes

PROTEINCHARGEDENSITY
Quantitative analysis of atomic polarization and protein-ligand electrostatic interactions via charge density studies in proteins: insights from ultra-high resolution crystallography

PTPS
Spatio-temporal regulation of growth factor signaling by PTPs in living cells

SIRT1 AND DIABETES***
Identification of the genes regulated by the SIRT1 histone deacetylase and their contribution in the pathogenesis of type 2 diabetes and obesity

SMART
Small molecule antagonists of chromatin modifying enzymes for regulation of transcription, proliferation and differentiation

TRANSHESC
Generation of stable transgenic embryonic stem cell lines


Research Area: ERC-AG /-SG

ADIPODIF***
Adipocyte differentiation and metabolic functions in obesity and type 2 diabetes

ALK7***
Metabolic control by the TGF-2 superfamily receptor ALK7: a novel regulator of insulin secretion, fat accumulation and energy balance

COMBINE
From flies to humans combining whole genome screens and tissue specific gene targeting to identify novel pathways involved in cancer and metastases

CONANX
Consumer culture in an age of anxiety: political and moral economies of food

DENDROWORLD
Mucosal dendritic cells in intestinal homeostasis and bacteria-related diseases

ICEBERG***
Discovery of type 2 diabetes targets


Research Area: ICT-2007

DIADVISOR***
Personal glucose predictive diabetes advisor

HEARTCYCLE
Compliance and effectiveness in HF and CHD closed-loop management

METABO***
Controlling chronic diseases related to metabolic disorders

TAS3
Trusted architecture for securely shared services


Research Area: INFRA-2007

EATRIS
European Advanced Translational Research InfraStructure in Medicine
http://www.eatris.eu


Research Area: KBBE-2007

ETHERPATHS
Characterization and modelling of dietary effects mediated by gut microbiota on lipid metabolism